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(8.1) Females of Reproductive Potential: Advise females using oral contraceptives to switch to a non-oral contraceptive method, or add a barrier method of contraception for 4 weeks after initiation and for 4 weeks after each dose escalation

Muchas clulas pueden secretar TC, la cual se combina con la B12 libre en las clulas del leon para formar holotranscobalamina (holoTC), que ingresa a la circulacin portal y ser la encargada de entregar la vitamina a las clulas, ya que transporta la fraccin funcional que puede ser absorbida por los tejidos y se libera rpidamente en ellos por endocitosis (proceso de incorporacin de molculas a las clulas) a travs de sus receptores especficos

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Additional ICD-10 codes may be required to capture underlying diseases, related disorders, or contributing conditions, following the correct sequencing and reporting guidelines