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Similarly, zinc released by MTs is capable of modulating the expression of antioxidant enzymes under the control of other zinc-modulated transcription factors

In PC9 cells, lysosomotropic agents enhanced ferroptosis induction with lower doses of GPX4 inhibitors (RSL3, ML162) (Fig

Notably, lysine acetylation plays a crucial role in regulating gene expression by modulating the chromatin structure, as acetylated histones are often associated with active transcription [51]

The acid acts at a posttranscriptional level on tyrosinase and tyrosinase-related protein

These actions demonstrate the ability of TRF to decrease ROS-induced negative effects, which are induced by the presence of lead in the body

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