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The most common of these are increased body fat (particularly abdominal fat), decreased lean body mass (including muscle), functional strength, thin skin and cool extremities, decreased psychological well-being and energy, reduced bone density, an increase in c-reactive protein, low-density lipoprotein (LDL), fibrinogen, plasminogen activator inhibitor-1 (PAI-1), a decrease in high-density lipoprotein (HDL), decreased insulin sensitivity, and decreased quality of life [25]

For example, in recurrent head and neck cancer, when organ sparring techniques are implemented, SBRT re-irradiation has demonstrated an acceptable toxicity profile and enhanced life quality outcomes

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Further, a notable single nucleotide polymorphism (SNP

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