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- GHK-Cu is a copper-binding research peptide studied in models involving skin biology, collagen-associated pathways, extracellular matrix research, wound-response signaling, hair follicle pathway models, angiogenesis, antioxidant response, and tissue-remodeling biology

Ethical approval This study was approved by the Ethics Committee of the Plastic Surgery Hospital (Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

Collagen deposited during the cycle remains

It is associated with supporting collagen and elastin production, helping improve firmness, elasticity, and overall skin quality

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therefore, potent cutaneous CYP3A4 inhibitors (e.g., ketoconazole shampoo left in place for prolonged periods) could conceivably elevate local finasteride levels, while strong inducers such as chronic topical corticosteroids may diminish effect