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and R is selected from the group consisting of an NH 2 moiety, alkyl moieties containing from 1 to 18 carbon atoms, aryl moleties containing from 6 to 12 atoms, alkoxy moleties containing from 1 to 18 carbon atoms, aryloxy moleties containing from 6 to 12 carbon atoms, alkylamino moieties containing from 1 to 18 carbon atoms, or where R is L-prolyl-L-valyl-L-phenylalanyl-L-valine, L-valyl-L-phenylalanyl-L-valine, L-tryptophan, or (glycyl)n-L-tryptophan where n=1-4

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Finally, we demonstrated that depletion of glutathione caused inhibition of the NF-kB pathway

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The agency further noted that while full FDA-approved indication is presented at the bottom of the ads, that is not enough to correct the overall misleading impression created by these claims. FDA issued another untitled letter to Amneal for misleading ads in its patient brochures for Alymsys injection for intravenous use