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Within each individual imaging site, mean values were compared using one-way ANOVA with time point as the fixed effect

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The treatment markedly reduced superoxide accumulation, preserved mitochondrial respiratory function, and attenuated systemic oxidative damage

Conclusion In summary, our findings demonstrate that the EZTG formula can improve embryo quality by reducing oxidative stress levels and decreasing GCs apoptosis through the activation of the Nrf2/HO-1 signaling pathway, thereby protecting the reproductive capacity of women of advanced age