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In the GI tract, commensals are immunologically protected by the resident Tregs that mediate luminal immunosuppression

338 Tumor cells also create an acidic microenvironment by exporting protons through Na/H exchangers and H/lactate cotransporters, which degrade the ECM and facilitate the formation of invasive protrusions

It is harvested from shells of shellfish and can be obtained from the consumption of shrimp, crab, lobster, and crayfish in trace amounts

( i-k ) Immunoblot of the indicated proteins in FT282 cells with empty vector (EV) or MYC overexpression treated with IDH1 inhibitor ( i ), cultured under glutamine starvation (GS) ( j ), or treated with mildronate ( k ) and supplemented with KG, l-carnitine, or O-acetyl-l-carnitine

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