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Here we aimed to achieve this outcome by targeting mitochondrial uncoupler compounds selectively to adipose tissue, thus avoiding side effects from uncoupling in other tissues

(PubMed) Al-Obaide MAI, Singh R, Datta P, et al

Finally, a major limitation is our lack of information about distribution of L-NAC and L-NACme in brain regions relevant to acquisition of opioid dependence

[DOI] [PubMed] [Google Scholar] [73].Yao XH, Ping YF, Bian XW, Contribution of cancer stem cells to tumor vasculogenic mimicry, Protein Cell 2 (4) (2011) 266272

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Therefore, when designing ER- or GA-targeted systems, the system should exploit differences between the ER and GA to exert drug efficacy immediately upon reaching the target organelle