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Designing pH-dependent systems based on nanoscale calcium carbonate for the delivery of an antitumor drug

Co-delivery of 2-deoxyglucose and a glutamine metabolism inhibitor V9302 via a prodrug micellar formulation for synergistic targeting of metabolism in cancer

Indeed, as mentioned in the Introduction, individuals with GPS may carry mutations that might cause a gain of an abnormal or dominant negative KAT6B protein function

Some evidence has been demonstrated that GSH is very poorly transported intact across the blood-brain barrier (BBB)

Nonetheless, in one infant with hyperammonaemia due to a suspected inborn error of metabolism, the use of a cocktail of intravenous nitrogen scavengers followed by sequential HD and haemofiltration successfully corrected the hyperammonaemia despite rapid clearance of the nitrogen scavengers by dialysis 31

Gorca A, Huk-Kolega H, Piechota A, Kleniewska P, Ciejka E, Skibska B