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[DOI] [PubMed] [Google Scholar] MacFarlane 2011 MacFarlane AJ, GreeneFinestone LS, Shi Y

This copper peptide gene regulation manifests in several clinically significant ways: Downregulation of Pro-Inflammatory Genes: It actively suppresses genes associated with inflammation, such as those in the IL-6 and NF-B pathways, which are major drivers of cellular aging

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Side Effects : NAD+ injections are generally well-tolerated, but some individuals may experience temporary redness, swelling, or pain at the injection site