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Oral B12 supplements face absorption barriers in the digestive system and may not effectively address severe deficiency

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This storage capacity means that deficiency symptoms often develop slowly, sometimes taking years to manifest after dietary intake becomes inadequate or absorption is compromised

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[248] Further, the study participants had persistent chronic low back pain, lasting a minimum of 90 days of conservative medical management that included at least medication and physical therapy, and they were not considered candidates for spine surgery

The goal is to build the foundational skills that support reading while also building confidence and motivation for reading activities