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The relationship between dietary MSG and metabolic findings were reviewed, and it is found that normal dietary MSG use is unlikely to influence energy intake, body weight or fat metabolism in animals and humans

PloS One 10, e0127462

Chem.-Int

Serum metabolomic profiling unveils distinct sex-related metabolic patterns in NAFLD

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indeed, glucose deprivation and/or hypoxia upregulate PRODH through AMP-activated protein kinase (AMPK), independent of HIF-1/2, leading to ROS generation, and consequently, to the activation of autophagy, which, in this context, exerts a pro-survival role