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Through the above experiments, we tentatively demonstrated that reduced expression of SIRT5 in DCM led to DCM-related injury and that Mal-Lys level was elevated in DCM and further enhanced after SIRT5 KO, closely correlating with DCM progression

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The following letter grades are based on the evidence quality criteria proposed by the American Academy of Pediatrics: A = well-designed RCTs or diagnostic studies on relevant populations

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Patients need comprehensive information on available treatments, including medications (GnRH agonists, IUDs, NSAIDs), minimally invasive procedures (focused ultrasound, uterine artery embolization), and surgical options like myomectomy or hysterectomy