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doi: 10.3389/fphys.2014.00372

Intracellular ROS levels were quantitatively measured using a 2,7-dichlorodihydrofluorescein diacetate (DCFH-DA) red or green fluorescent probe, as previously reported 52

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PHGPxs role in many tissues has been described, including protection against oxidative stress against spermatozoa in the testes, as well as its neuroprotective properties illustrated by the link between GPx4 deficiency and Alzheimers and Parkinsons dementia [66]

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Pharmacologic or genetic targeting of glutamine synthetase skews macrophages toward an M1-like phenotype and inhibits tumor metastasis