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Glutathione S-Transferases in Cancer

Reis, Z

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-It is a natural supplement considered non-toxic, and, therefore, its consumption, in the doses we recommend, is completely safe

The equine neutrophilic proteinase inhibitors share their target specificity with eNAP-2, but in contrast they were stable at temperatures up to 100C and the inhibitory activity remained constant at a broad pH-range

By directly disabling the enzymatic constraint on ferroptotic execution, they ensure irreversible lipid peroxide accumulation, positioning GPX4 inhibition as a powerful and non-redundant entry point for therapeutic intervention in redox-driven malignancies