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Enhanced lipid-centric adaptation results in a metabolic switch, shifting MDSCs away from glycolytic metabolism toward FAO to ensure an ample supply of energy intermediates and bioactive lipid mediators to potentiate their immunosuppressive activity and longevity (72)

*RI = Reference Intake

5A), cumulatively, Actinobacteria was the most abundant (42.24% 13.86%), followed by Firmicutes (35.38% 11.81%), Bacteroidetes (17.84% 6.71%), Euryarchaeota (2.83% 1.63%) and Proteobacteria (1.23% 1.76%), which explained the 99.5% of the phylum-level bacterial diversity

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Hormonal fluctuations, particularly during pregnancy or menopause, may also initiate or exacerbate Graves' disease