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Some drugs and chemicals, however, are predictably injurious for all G6PD-deficient subjects, 3 , 30 and these agents are listed in Table 28.2

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By potentially reducing the presence and impact of senescent cells, FOXO4-DRI might thereby restore tissue homeostasis and reduce biomarkers of cell aging

10.1016/j.physbeh.2015.12.008 203 LabunskyyV

The primary BAs are then metabolized and transformed by the gut microbiota through a series of reactions, including deconjugation, dehydroxylation, oxidation and epimerization, to generate secondary BAs (Cai et al., 2022