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Rapid birth-death evolution and positive selection in detoxification-type glutathione S-transferases in mammals

These steps are catalyzed by dihydrouracil dehydrogenase (dihydropyrimidine dehydrogenase), dihydropyrimidinase (dihydropyrimidine amidohydrolase), and 3-ureidopropionase (-alanine synthase), respectively [11,20,26,27]