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No form is universally superior, and clinical data is still evolving

[ 2 ] Investigators isolated the peptide from the cerebral venous blood of rabbits that had been induced to sleep through electrical stimulation of a specific brain region called the intralaminar thalamus

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Goldstein AL, Kleinman HK

Dose-escalation schedules appeared to improve tolerability compared to fixed higher-dose groups

Compared to placebo, it has been shown to significantly lower HbA1c by up to 2.07% when administered as a once-weekly subcutaneous injection at a maximum dose of 15 mg