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Elevated iron levels promote ROS production, depleting intracellular GSH levels and accelerating lipid peroxidation

Low glutathione-to-GSSG ratios suggest higher oxidative burden and may warrant twice-daily dosing rather than single-dose protocols

The shared core pathways include hyperglycemia, dyslipidemia, hemodynamic alterations, oxidative stress, the formation of advanced glycation end products (AGEs) and chronic inflammation

Other good sources of riboflavin include eggs, leafy vegetables, broccoli, milk, legumes, mushrooms and meat