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Both cortisol and cortisone levels follow a daily rhythm, peaking in the morning (daytime) and corresponding with the maternal hypothalamic-pituitary-adrenal axis activity [49]

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It is positively correlated with zinc accumulation, thereby conferring a protective effect against excess zinc-induced cytotoxicity

20 Pharmacological inhibition or genetic absence of GPX4 induce ferroptosis in mouse tumor xenografts

The structure of mammalian GPXs was also analyzed by computer-assisted molecular modelling

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