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Thus, a diminished activity of the Prdx2 antioxidant system may be a contributor to G6PD-related diseases, and this could also be dependent on the G6PD genetic variant

Modern liver-specific IGF-1 knockout studies have shown that local IGF-1 contributes substantially to tissue IGF1R activation, separate from the endocrine pool

NAD+ may help to boost metabolism by increasing the activity of certain enzymes involved in energy production

for 1, 3, or 7 days) decreased spinal cord oxidative stress biomarkers in rats with neuropathic pain [181]

The term caspase is based on a common nomenclature universally adopted: 'c' reflects a cysteine protease mechanism, and 'aspase' refers to the ability of these proteases to cleave a protein following an aspartic acid residue [127129]

Recently, we introduced the pegylated imidazodiazepine (PI320) and found that the addition of a pentaethylene glycol substitution did only marginally reduce the affinity of GABA(A) receptors (Zahn et al