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Reduced Ca2+ entry and suicidal death of erythrocytes in PDK1 hypomorphic mice

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In turn, villous atrophy can impair nutrient absorption and is one of the primary mechanisms underpinning extensive nutritional deficiencies found in Celiac and inflammatory bowel diseases (198)

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Mitochondrial dynamics control the copy number of mtDNA, while the maintenance of mtDNA copy number is attributed to mitochondrial fusion