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It is a tripeptide with gamma peptide linkage between the carboxyl group of the glutamate side-chain and the amine group of cysteine, and the carboxyl group of cysteine is attached by a normal peptide linkage to a glycine

Research shows that grapefruit juice can increase the bioavailability of oral budesonide by around 1.5 to 2 times

Modern Catalytic Methods for Organic Synthesis with Diazo Compounds (From Cyclopropanes to Ylides) (Wiley-Interscience Press, New York, 1998)

Sauerbeck, A., Schonberg, D

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Therefore, we conclude, in agreement with the study by Di Gennaro et al., [50] that LTC4S plays a critical role as a potential rate-limiting factor in the final phase of LTC4 synthesis and subsequently for other CysLTs