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Description

2013;144(5):S999

Rather than blocking KRAS activity, PROTACs induce selective degradation of the target protein by recruiting E3 ubiquitin ligases and triggering proteasomal destruction

Corduk M, Sarica S

However, C4 was more strongly associated with breast cancer among individuals with a luminal B-like (HER2-positive or negative) subtype than other surrogate subtypes