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A response observed in one model should therefore not be generalized to another model without confirming transporter context, intracellular carnitine status, and functional oxidation readouts

For more details, see reference ( The final section will focus on the MM environment, with particular attention to the bone marrow (BM) niche, aiming to identify new players and leverage their unique properties to enhance tumor eradication

Testing increasing concentrations of DZnep on these transgenic embryos revealed clear similarity to the effects of DZnep on circadian clock markers, resulting in the lengthening of the somite segmentation clock period (Supplementary Fig

Thus, mitochondria are tightly linked to NAD(H) turnover (Gakire et al., 2018a)

Subsequently, we will elucidate the effect of iron overload on the pathophysiology of MDS and AML, clinical consequences of the altered iron metabolism and its use as a potential target for therapy

Dahlof C, Bjorkman R