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demonstrated that Mtb infection induced a reduction of sirtuin 1 expression in macrophages and mouse models with NF-B overexpression (149)

IGF2 mRNA expression is increased in prostate cancer during progression to castration-resistant disease [111]

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Results Among 218 patients with available TMAO measurements, those in higher quartiles showed an increased all-cause mortality compared to the lowest quartile after 180 days (adjusted HR 1.92 95% CI 1.033.56, p = 0.04) and 5 years (adjusted HR 2.01 95% CI 1.233.31, p = 0.006)

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