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In line with BSSM guidance and testosterone SmPCs (e.g., Nebido), TRT should be paused or the dose reviewed if haematocrit exceeds 0.54

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The rationale is that AOD 9604 preferentially targets adipose tissue, which might help shift the composition of weight loss more toward fat and away from lean mass

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This dialogue can lead to tailored strategies, such as dietary modifications, hydration, and possibly the use of over-the-counter remedies, to alleviate symptoms and improve overall quality of life while on GLP-1 medications