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The Connectivity Map analysis cited by Campbell, Pickart, and Margolina found that GHK affects approximately 31 percent of analyzed human genes, with the net pattern resetting age-shifted gene expression toward younger profiles 8 9

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Modulation of 4,000+ genes (the gene reset hypothesis) In 2012, Pickart and Margolina published a landmark transcriptomic analysis , they tracked which genes GHK-Cu changes in fibroblasts

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