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While Vitamin D and C are essential for joint maintenance, advanced conditions like osteoarthritis of the knee may require procedures like Genicular Artery Embolization to address chronic inflammation.

People taking long-term metformin are at particular risk of B12 deficiency, as metformin impairs B12 absorption in the terminal ileum

Ventrogluteal: Above and to the outside of the buttock area, on the hip

Stress & hydration: Manage stress and stay well hydrated, especially if GI side effects reduce intake

Type 2 pernicious anemia, which is less frequent than Type 1, can result from mutations in genes related to the transport of vitamin B12

Biological Targets for Weight-Loss Drug Development Figure 2: Simplified schematic overview of biological pathways targeted by weight-management drugs 3