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Cell 155, 285295

This may be in part due to Y box binding protein 1 (YBX1), which has a dual role in SGs and EVs [31,32,33]

One ml, 300 l, or 120 l of bacterial concentrate were added to 15 cm, 6 cm, or 3.5 cm plates, respectively

Post hoc multiple comparisons were made using the Tukey-Kramer test

Thus far, approximately 40 companies worldwide, including Codiak Biosciences, Evox Therapeutics, Tavec Pharmaceuticals, Carmine Therapeutics, Anjarium, and Micromedmark Biotech, have developed exosome-based therapies, which are expected to provide cost-effective and more accurate targeted therapies in the clinic ( However, challenges, such as large-scale production, purity, and batch homogeneity of exosomes, still limit their clinical application

Dilshara MG, Jeong JW, Prasad Tharanga Jayasooriya RG, Neelaka Molagoda IM, Lee S, Park SR, Choi YH, Kim GY