glutathione switch persister cells Ferroptosis Dependence in Drug-Tolerant Cells👇 ✓Chemotherapy or BH3 mimetics trigger mitochondrial outer membrane permeabilization (miMOMP) in a subset of cancer cells. Instead of undergoing full apoptosis, these survive the initial Frontiers | Drug-tolerant persister cells
Frontiers Drug tolerant persister cells in acute myeloid leukemia: pressing challenge and promising new strategies for treatment Glutathione responsive nanomedicine leverages tumor redox imbalance for targeted cancer theranostics Discover Oncology Springer Nature Link Cancer drug tolerant persister cells: from biological questions to clinical opportunities Nature Reviews Cancer Cellular Compartmentalization, Glutathione Transport and Its Relevance in Some Pathologies Additional data demonstrating that persister cells have a disabled Download Scientific Diagram Frontiers Drug tolerant persister cells: the deadly survivors in hematological malignancies
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