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Annu Rev Med 59:267280 Heiss E, Herhaus C, Klimo K, Bartsch H, Gerhauser C (2001) Nuclear factor kappa B is a molecular target for sulforaphane-mediated anti-inflammatory mechanisms

Finally we examined whether individuals with CLD and a high polygenic risk score (PRS) for cirrhosis (e.g., top 5th percentile) were at increased risk of cirrhosis, HCC, and liver mortality using multi-state Markov survival models using the transitional states of CLD, cirrhosis, HCC, and liver mortality over a 20 year follow-up period in 134,841 Europeans (EUR), 20,068 Hispanics (HIS), and 39,397 African Americans (AA) in MVP