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Receptor Profile : Cagrilintide acts as a nonselective agonist at amylin receptors (AMY1/2/3) and the calcitonin receptor, which are involved in appetite regulation, gastric emptying, and energy homeostasis

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N Engl J Med 2020;383:1735-45

NICE TA875 specifies that treatment should be reviewed at two years, with continuation only where clinically appropriate within the terms of the appraisal