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Germ-free mice or those with altered microbiota show changes in gut eosinophil numbers, suggesting microbiota-derived signals (such as microbial metabolites) help set basal eosinophil levels ( Recent findings have highlighted the role of tuft cells in the intestinal epithelium as key initiators of type 2 immunity involving eosinophils

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Firmer skin As tretinoin boosts collagen production, some users may notice their skin becoming firmer and more youthful 13