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Persistent higher activity (neuronal excitation) caused by chronically increased extracellular glutamate, combined with higher metabolic/energy needs, could then produce a critical state potentially resulting in neuronal death

How Glutathione Works: Your Bodys Master Detoxifier Glutathione is a naturally occurring antioxidant found in every cell of your body, with particularly high concentrations in the liver

PMID: 182 JiangCXieSYangGWangN

doi: 10.1016/j.biomaterials.2013.04.064

According to clinicians, sublingual administration bypasses both the gut and the liver, allowing glutathione to enter the bloodstream in its reduced (active) form, boosting the ratio of GSH to GSSG by 230 per cent, whereas oral glutathione supplementation is either reduced into simple amino acids during digestion or oxidised and hence, no longer stays active when swallowed

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