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Three major metabolic pathways are involved in ceramide biosynthesis: the de novo, the salvage pathway and the sphingomyelinase pathway

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Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor

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The present study showed that protection of mitochondria from overload not only rescues tendon cells themselves but also improves the immune microenvironment, which highlights the potential of mitochondria treatment for tendinopathy