chac1 er stress glutathione degradation Peroxidase 8 Suppression by Histone Deacetylase Inhibitors Enhances Endoplasmic Reticulum and Cell Death by Oxidative Stress in Hepatocellular Carcinoma Cells CHAC1 degradation of glutathione enhances

CHAC1 degradation of glutathione enhances cystine starvation induced necroptosis and ferroptosis in human triple negative breast cancer cells via the GCN2 eIF2 ATF4 pathway Oncotarget Long noncoding RNA GDIL acts as a scaffold for CHAC1 and XRN2 to promote platinum resistance of colorectal cancer through inhibition of glutathione degradation Cell Death & Disease Glutathione specific gammaglutamylcyclotransferase 1 (CHAC1) increases kidney disease risk by modulating ferroptosis Science Translational Medicine ChaC1 based drug screenings identify a synergistic lethal effect of auranofin and proteasome inhibitors in hepatocellular carcinoma cells Cell Death Discovery CHAC1: a master regulator of oxidative stress and ferroptosis in human diseases and cancers PMC Endoplasmic reticulum stress: molecular mechanism and therapeutic targets Signal Transduction and Targeted Therapy

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