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5 In-depth exploration of specific glycolipid metabolism markers and disease activity in RA 5.1 Association of glycolysis-specific markers with RA disease activity The abnormal expression of glycolysis-related key enzymes and their metabolites shows a significant correlation with disease activity and progression of bone destruction during the pathological process of RA

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This review systematically elucidates the prevailing diagnostic criteria, summarizes recent advances in understanding the potential pathophysiological mechanisms, and evaluates pharmacological and non-pharmacological interventions, and symptom-based assessment and management strategies