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Local delivery, distribution, and anti-metastatic effects of si-PGC-1 LNP in metastatic bladder cancer To evaluate the uniform distribution of siRNA in a mouse bladder cancer model, we injected si-PGC-1 LNP into subcutaneous xenografts

Aggregated AGEs can activate the JNK, I-B kinase (IKK), NF-B, and TNF- pathways to trigger hypothalamic insulin and leptin resistance, resulting in hypothalamic dysfunction, imbalanced energy control, and subsequently elevated food consumption and body weight with obesity and metabolic syndromes 78

The role of TNFalpha and lymphotoxin in demyelinating disease

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[DOI] [PubMed] [Google Scholar] 73.Jagannath V.A., Fedorowicz Z., Al Hajeri A., Sharma A

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