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Interestingly, miR-206 expression was higher in the hippocampus, plasma, and CSF of APP/PS1 mice as compared to wild-type (WT) mice, whereas BDNF level was lower in the hippocampal tissue, plasma, and CSF of APP/PS1 mice than in WT mice

doi: 10.1292/jvms.18-0250

For example, NR3C1-1F DNA methylation was found reduced in patients with ME/CFS and coincides with the hypothalamic pituitary-adrenal (HPA) axis hypofunction hypothesis (75)