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In contrast, although ovarian-specific transcripts exhibit moderate enrichment in fundamental reproductive processes such as meiotic nuclear division (GO:1903046), reproductive processes (GO:0019953), and Wnt signaling pathway (GO:0022414), their predominant functional roles converge on stem cell differentiation, neural crest cell development, and stress-response pathways (Figure 2D)

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Using artificial intelligence to improve public health: a narrative review

10.1161/CIRCULATIONAHA.117.031264 5

By inhibiting the activity of system Xc , sorafenib blocks the transport of cystine/glutamate, leading to endoplasmic reticulum stress, impaired GSH synthesis, disruption of intracellular redox homeostasis and accumulation of lipid ROS, thereby inducing ferroptosis [17]

Tate SS, Meister A