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Physiological redox signaling operates within defined spatial and temporal limits, whereas sustained ROS overproduction overwhelms antioxidant buffering systems and causes lipid peroxidation, protein carbonylation, DNA damage, and neuronal dysfunction

Among the various definitions of sarcopenia, this study utilized the SMI criteria validated in Asians [14]

48 Mice deficient in ASC, NLRP3, or caspase-1 fail to demonstrate significant protection against APAP-induced liver injury

Therefore, exercise-induced lactate is detected through a brain receptor and produces angiogenic effects in the brain

NAF-1 inhibition by resveratrol suppresses cancer stem cell-like properties and the invasion of pancreatic cancer