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Measurement of GSH concentration HepG2 cells were treated with BSO and/or NAC as described above and then exposed to different concentrations of ASA for 48 h

At 1 mM extracellular NH 4 Cl it amounted to 30 nmol/mg protein per min, which in vivo (100 g protein/g wet wt.) would equal 3 mol/g wet wt per min, or about one half of the in vivo rate of the glutamineglutamate (GABA) cycle (Table 1)

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Antibody-drug conjugates for ovarian cancer: current clinical development