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But as Herman Waldmann, one of Lefkovits' collaborators, points out the weakness with their method was that it 'was looking downstream of the original precursor cell.' The difficulty was that they had shown the plasma cell made only one antibody without establishing precommitment to an antigen on the part of precursor or parent cells

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5 a,b,c, reveal a pronounced concentration-dependent and time-dependent antifungal effect

Where the gaps still are

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PMID 24533607