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Results Peptides Having the Sequences of Various SNARE Motifs To search for potent peptide inhibitors that can interfere with SNARE complex formation and thereby reduce mast cell degranulation, seventeen 17-mer peptides were synthesized of which sequences were patterned after the N-terminal (N), middle (M), and C-terminal (C) regions of the SNARE motifs of SNAP-23 (SN23 and SC23), Syn4, and VAMPs (Vp2, 4, 7, and 8) (Table 1

doi: 10.1016/j.phymed.2020.153454

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In our current experience, we are treating about 50 PD patients with similar multimodal therapy