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3 (compounds 3742 and compound 4348 ) were replaced by the furan and thiophene ring

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Dermatological side effects of allopurinol range from a mild morbilliform eruption (measles-like rash, which resolves when the drug is discontinued) to Stevens-Johnson syndrome / toxic epidermal necrolysis and drug hypersensitivity syndrome

Garcia-Marchena N, Silva-Pena D, Martin-Velasco AI, Villanua MA, Araos P, Pedraz M, Maza-Quiroga R, Romero-Sanchiz P et al (2017) Decreased plasma concentrations of BDNF and IGF-1 in abstinent patients with alcohol use disorders

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