chac1 glutathione Glutathione-specific gamma–glutamylcyclotransferase 1 (CHAC1) increases kidney disease risk by modulating ferroptosis Glutathione (GSH) depletion by ChaC1

Glutathione (GSH) depletion by ChaC1 results in a more oxidizing Download Scientific Diagram Calcium channel mutants rescue the effect of glutathione depletion. (A) Download Scientific Diagram Mitochondrial respiratory function is preserved under cysteine starvation via glutathione catabolism in NSCLC Nature Communications journal club Kidney International Long noncoding RNA GDIL acts as a scaffold for CHAC1 and XRN2 to promote platinum resistance of colorectal cancer through inhibition of glutathione degradation Cell Death & Disease CHAC1 inactivation is effective to preserve muscle glutathione but is insufficient to protect against muscle wasting in cachexia PLOS One

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