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Transfection of GRM1 induces transformation of mouse kidney cells that exhibit enhanced cell proliferation in vitro and significant tumorigenicity in vivo involving MAPK and AKT signaling, both crucial for tumorigenesis (141)

Our study also supports previous findings that tumors in the lower outer quadrant of the breast are associated with better prognosis 48

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patients should be monitored more frequently for myelosuppression, renal toxicity, and gastrointestinal toxicity if concurrent ibuprofen cannot be avoided