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SOCS-3 is an insulin-induced negative regulator of insulin signaling

The molecular mechanisms underlying OIPN are complex, with multi-targets and various cells causing neuropathy

10.3109/09513590.2012.706668 70 LiC.ZhaoH

Riluzole remains the main approved therapy for ALS, despite yielding only modest survival gains through partial attenuation of glutamatergic excitotoxicity [7073]